Biocompatibility study of lithium disilicate and zirconium oxide ceramics for esthetic dental abutments
Brunot-Gohin Celine, Duval Jean-Luc, Verbeke Sandra, Belanger Kayla, Pezron Isabelle, Kugel Gerard, Laurent-Maquin Dominique, Gangloff Sophie, Egles Christophe,
소속 상세정보
( Brunot-Gohin Celine ) - University of Reims Champagne-Ardenne Laboratory of Biomaterials and Bone Site Inflammation
( Duval Jean-Luc ) - Sorbonne Universities University of Technology of Compiegne Laboratory of Biomechanics and Bioengineering
( Verbeke Sandra ) - University of Reims Champagne-Ardenne Faculty of Odontology
( Belanger Kayla ) - Sorbonne Universities University of Technology of Compiegne Laboratory of Biomechanics and Bioengineering
( Pezron Isabelle ) - Sorbonne Universities University of Technology of Compiegne Laboratory of Integrated Renewable Matter Transformations
( Kugel Gerard ) - Tufts University School of Dental Medicine
( Laurent-Maquin Dominique ) - University of Reims Champagne-Ardenne Laboratory of Biomaterials and Bone Site Inflammation
( Gangloff Sophie ) - University of Reims Champagne-Ardenne Laboratory of Biomaterials and Bone Site Inflammation
( Egles Christophe ) - Sorbonne Universities University of Technology of Compiegne Laboratory of Biomechanics and Bioengineering
KMID : 0363020160460060362
Abstract
Purpose: The increasing demand for esthetically pleasing results has contributed to the use of ceramics for dental implant abutments. The aim of this study was to compare the biological response of epithelial tissue cultivated on lithium disilicate (LS2) and zirconium oxide (ZrO2) ceramics. Understanding the relevant physicochemical and mechanical properties of these ceramics will help identify the optimal material for facilitating gingival wound closure.
Methods: Both biomaterials were prepared with 2 different surface treatments: raw and polished. Their physicochemical characteristics were analyzed by contact angle measurements, scanning white-light interferometry, and scanning electron microscopy. An organotypic culture was then performed using a chicken epithelium model to simulate peri-implant soft tissue. We measured the contact angle, hydrophobicity, and roughness of the materials as well as the tissue behavior at their surfaces (cell migration and cell adhesion).
Results: The best cell migration was observed on ZrO2 ceramic. Cell adhesion was also drastically lower on the polished ZrO2 ceramic than on both the raw and polished LS2. Evaluating various surface topographies of LS2 showed that increasing surface roughness improved cell adhesion, leading to an increase of up to 13%.
Conclusions: Our results demonstrate that a biomaterial, here LS2, can be modified using simple surface changes in order to finely modulate soft tissue adhesion. Strong adhesion at the abutment associated with weak migration assists in gingival wound healing. On the same material, polishing can reduce cell adhesion without drastically modifying cell migration. A comparison of LS2 and ZrO2 ceramic showed that LS2 was more conducive to creating varying tissue reactions. Our results can help dental surgeons to choose, especially for esthetic implant abutments, the most appropriate biomaterial as well as the most appropriate surface treatment to use in accordance with specific clinical dental applications.
키워드
Ceramics; Dental abutments; Dental esthetics; Embryo culture techniques
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